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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYLK2 All Species: 20.91
Human Site: Y500 Identified Species: 57.5
UniProt: Q9H1R3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1R3 NP_149109.1 596 64685 Y500 N V L S G N W Y F D E E T F E
Chimpanzee Pan troglodytes XP_527218 388 44535 L316 A E T L N N I L A C R W D L E
Rhesus Macaque Macaca mulatta XP_001113601 819 88691 D730 F I V N C S W D F D A D T F E
Dog Lupus familis XP_534377 634 68610 Y538 N V L S S N W Y F D E E T F E
Cat Felis silvestris
Mouse Mus musculus Q8VCR8 613 65971 Y517 N V L S A N W Y F D E E T F E
Rat Rattus norvegicus P20689 610 65798 Y514 N V L S A N W Y F D E E T F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521045 729 77615 D640 F I V N C S W D F D A E A F E
Chicken Gallus gallus NP_990723 825 87195 Y729 N V L A A N W Y F D E E T F E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103990 555 61596 Y482 N V L M G N W Y F D E D A F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.2 37.8 81.6 N.A. 80.9 80.8 N.A. 41.9 48.4 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 49.5 50.9 86.1 N.A. 85.1 85.4 N.A. 54.7 58.2 N.A. 56.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 40 93.3 N.A. 93.3 93.3 N.A. 40 86.6 N.A. 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 73.3 93.3 N.A. 93.3 93.3 N.A. 66.6 93.3 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 34 0 0 0 12 0 23 0 23 0 0 % A
% Cys: 0 0 0 0 23 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 23 0 89 0 23 12 0 0 % D
% Glu: 0 12 0 0 0 0 0 0 0 0 67 67 0 0 100 % E
% Phe: 23 0 0 0 0 0 0 0 89 0 0 0 0 89 0 % F
% Gly: 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 23 0 0 0 0 12 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 67 12 0 0 0 12 0 0 0 0 0 12 0 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 67 0 0 23 12 78 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % R
% Ser: 0 0 0 45 12 23 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 12 0 0 0 0 0 0 0 0 0 67 0 0 % T
% Val: 0 67 23 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 89 0 0 0 0 12 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _